Risk Factors for Cardiovascular Events in Patients on Antidementia Medications

American Journal of Alzheimer's Disease &Other Dementiasr, Volume 35, Issue , January-December 2020. Objective:To identify characteristics associated with an increased risk of cardiovascular events in patients diagnosed with Alzheimer disease (AD) and treated with antidementia medications.Methods:Demographics, diagnoses, and medication usage of 30 433 Medicare patients were analyzed using 2006 to 2013 claims data and a combined model of screening, ranking and stepwise logistic regressions t...
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Association Between Subjective Cognitive Decline and Social and Emotional Support in US Adults

American Journal of Alzheimer's Disease &Other Dementiasr, Volume 35, Issue , January-December 2020. Subjective cognitive decline (SCD) has been linked to Alzheimer’s Disease in the literature. However, little is known about whether SCD is associated with social/emotional support (SES). To investigate this association, this study utilized the 2015 and 2016 Behavioral Risk Factor Surveillance System data. A study population of 17206 participants aged 45 years and older who responded to both ...
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A Metabolic Imaging Study of Lexical and Phonological Naming Errors in Alzheimer Disease

American Journal of Alzheimer's Disease &Other Dementiasr, Volume 35, Issue , January-December 2020. Patients with Alzheimer disease (AD) produce a variety of errors on confrontation naming that indicate multiple loci of impairment along the naming process in this disease. We correlated brain hypometabolism, measured with 18fluoro-deoxy-glucose positron emission tomography, with semantic and formal errors, as well as nonwords deriving from phonological errors produced in a picture-naming te...
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Evaluating Semantic Knowledge Through a Semantic Association Task in Individuals With Dementia

American Journal of Alzheimer's Disease &Other Dementiasr, Volume 35, Issue , January-December 2020. Conceptual knowledge is supported by multiple semantic systems that are specialized for the analysis of different properties associated with object concepts. Various types of semantic association between concrete concepts—categorical (CA), encyclopedic (EA), functional (FA), and visual-encyclopedic (VEA) associations—were tested through a new picture-to-picture matching task (semantic associ...
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Whole-Blood Levels of MicroRNA-9 Are Decreased in Patients With Late-Onset Alzheimer Disease

American Journal of Alzheimer's Disease &Other Dementiasr, Volume 35, Issue , January-December 2020. Recent evidence suggests changes in circulating microRNA levels may be promising biomarkers for the clinical diagnosis of Alzheimer disease (AD). We hypothesized that whole-blood microRNAs may be useful to identify individuals with established AD. For this purpose, a sample of community-dwelling women (≥55 years old) carrying the ApoE ∊4 allele were clinically evaluated using the American Ps...
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Loneliness and Burden Perceived by Family Caregivers of Patients With Alzheimer Disease

American Journal of Alzheimer's Disease &Other Dementiasr, Volume 35, Issue , January-December 2020. Background:The present study aimed at investigating loneliness and burden experienced by family members caring for relatives diagnosed with Alzheimer disease.Methods:Participants were 40 caregivers of inpatients with Alzheimer disease. Correlation and multiple regression analyses were conducted to investigate whether caregivers’ loneliness (uni- and multidimensional) and burden are associate...
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