Relationship between Alzheimer’s and Diabetes

The drugs used to treat diabetes could also be used to treat Alzheimer's, and vice versa, if the results of new research from the University of Aberdeen in the UK are confirmed. UK – The study shows that Alzheimer’s disease and type 2 diabetes are linked so closely that the drugs used to control glucose levels in the latter could also relieve symptoms and progression of the first. The research, published in the journal Diabetologia, first found that complications related to dementia in the brai...
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Memory Restoration In Alzheimer’s Patients

A new research has revealed the first of its kind success in treating Alzheimer's memory restoration in early Alzheimer's disease (AD) or its precursors. Exceptional progress has been noted in the outcomes of quantitative MRI and neuro-psychological testing. The tests were performed after the ten participating patients underwent a treatment involving a programmatic and personalized therapy. New technique The new technique was named metabolic enhancement for neuro-degeneration. The outc...
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Cognitive Reserve in Healthy Aging and Alzheimers Disease: A Meta-Analysis of fMRI Studies

Cognitive reserve (CR) has been defined as the ability to optimize or maximize performance through differential recruitment of brain networks. In the present study, we aimed at providing evidence for a consistent brain network underpinning CR in healthy and pathological aging. To pursue this aim, we performed a coordinate-based meta-analysis of 17 functional magnetic resonance imaging studies on CR proxies in healthy aging, Alzheimer’s disease (AD), and mild cognitive impairment (MCI). We...
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Neural Underpinnings of the Decline of Topographical Memory in Mild Cognitive Impairment

Spatial navigation is one of the cognitive functions known to decline in both normal and pathological aging. In the present study, we aimed to assess the neural correlates of the decline of topographical memory in patients with amnestic mild cognitive impairment (aMCI). Patients with aMCI and age-matched controls were engaged in an intensive learning paradigm, lasting for 5 days, during which they had to encode 1 path from an egocentric perspective and 1 path from an allocentric perspective. Af...
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The Effect of Undiagnosed Diabetes on the Association Between Self-Reported Diabetes and Cognitive Impairment Among Older Mexican Adults

Purpose:To study the effect of undiagnosed diabetes on the relationship between self-reported diabetes and cognitive impairment.Methods:Data were from 1033 participants aged ≥60 from Wave III (2012) of the Mexican Health and Aging Study. Participants were classified as nondiabetic (n = 589), undiagnosed diabetic (n = 201), and self-reported diabetic (n = 243). Multivariate logistic regression models were used to estimate the relationship between self-reported diabetes and severity of cogniti...
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A Quasi-Randomized Controlled Trial of Brain-Activating Rehabilitation in an Acute Hospital

We aimed to confirm the effectiveness of brain-activating rehabilitation (BAR) performed in the day care setting at an acute hospital. Brain-activating rehabilitation is based on 5 principles: developing a pleasant atmosphere, promoting communication, praising patients, giving patients a social role, and providing supportive care. A total of 48 patients with dementia or cognitive impairment were selected and randomly divided into the intervention and control groups. The BAR-based intervention w...
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