The Effect of Hormone Replacement Therapy on Cognitive Function in Female Patients With Alzheimer's Disease: A Meta-Analysis

American Journal of Alzheimer's Disease &Other Dementiasr, Volume 35, Issue , January-December 2020. Previous studies have indicated that estrogen may delay disease progression and minimize the cognitive decline in patients with Alzheimer's disease (AD). However, the evidence for an estrogen deficiency in women with dementia and cognitive dysfunction is inconsistent. In the present review, a fixed effect meta-analysis revealed that the hormone replacement therapy (HRT) group exhibited signi...
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Differential Association of Aggression With Sadness for People With Moderate and Severe Dementia

American Journal of Alzheimer's Disease &Other Dementiasr, Volume 35, Issue , January-December 2020. Little is known about how individual behavioral and psychological symptoms of dementia (BPSD) impact the person with dementia. This cross-sectional, retrospective study examined the association between one BPSD, aggressive behavior, and a patient-identified outcome, sadness, among people with moderate and severe dementia (n = 5001) using clinical administrative Resident Assessment Instrument...
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An Automated Approach to Examining Pausing in the Speech of People With Dementia

American Journal of Alzheimer's Disease &Other Dementiasr, Volume 35, Issue , January-December 2020. Dementia is a common neurodegenerative condition involving the deterioration of cognitive and communication skills. Pausing in the speech of people with dementia is a dysfluency that may be used to signal conversational trouble in social interaction. This study aimed to examine the speech-pausing profile within picture description samples from people with dementia and healthy controls (HCs) ...
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Practicality Assessment of the Improved ICT-Based Dementia Care Mapping Support System

American Journal of Alzheimer's Disease &Other Dementiasr, Volume 35, Issue , January-December 2020. Objectives:Authors have developed an ICT (Information-Communication Technology)-based Dementia Care Mapping (DCM™) support system and assessed its usefulness previously using videos. The aim of this study is to evaluate practicality of the improved support system by actual mapping.Methods:We obtained highly reliable mapping data by a team of 3 mappers (M1, M2, and M3), who mapped 5 elderly p...
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PSP-FTD Complex: A Possible Variant of PSP

American Journal of Alzheimer's Disease &Other Dementiasr, Volume 35, Issue , January-December 2020. Introduction:This study tried to find out type of lobar features found in patients with progressive supranuclear palsy (PSP) and whether they differ from those of frontotemporal dementia (FTD) as both of these are tauopathies.Methods:We studied lobar functions of 45 patients with PSP.Results:Five (11.1%) patients had no lobar feature; 11 (24.4%) had PSP-like features like apathy, frontal rel...
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New-Onset Alzheimer’s Disease and Normal Subjects 100% Separated Statistically by P300 and ICA

American Journal of Alzheimer's Disease &Other Dementiasr, Volume 35, Issue , January-December 2020. Previously, we described how patients with new-onset Alzheimer’s disease were differentiated from healthy, normal subjects to 100% accuracy, based on the amplitudes of the nonrhythmic back-projected independent components of the P300 peak at the electroencephalogram electrodes and their latency in the response to an oddball, auditory evoked potential paradigm. A neural network and a voting s...
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