Classification of Dementia Severity in Taiwan Based on History-Based Clinical Diagnosis System

American Journal of Alzheimer’s Disease &Other Dementiasr, Volume 35, Issue , January-December 2020.
Background/Aims:This study used HAICDDS screening questionnaire to classify the severity of dementia in Taiwan based on the clinical dementia rating scale.Methods:LDA was applied to 6,328 Taiwanese clinical patients for classification purposes. Clustering method was used to identify the associated influential symptoms for each severity level.Result:LDA shows only 36 HAICDDS questions are significant to distinguish the 5 severity levels with 80% overall accuracy and it increased to 85.83% when combining normal and MCI groups. Severe dementia patients have the most serious declination in most cognitive and functionality domains, follows by moderate dementia, mild dementia, MCI and normal patients.Conclusion:HAICDDS is a reliable and time-saved diagnosis tool in classifying the severity of dementia before undergoing a more in-depth clinical examination. The modified CDR may be indicated for epidemiological study and provide a solid foundation to develop a machine-learning derived screening instrument to detect dementia symptoms.Classification of Dementia Severity in Taiwan Based on History-Based Clinical Diagnosis SystemClassification of Dementia Severity in Taiwan Based on History-Based Clinical Diagnosis SystemAlzheimers{$excerpt:n}