Experiences of Living With Primary Progressive Aphasia: A Scoping Review of Qualitative Studies

American Journal of Alzheimer's Disease &Other Dementias®, Ahead of Print. Introduction:Understanding the experiences of people who live with primary progressive aphasia (PPA) can inform the development of appropriate speech-language pathology services for this population. This review aimed to summarize the qualitative research on the experience of living with PPA from the perspective of the individuals with the disorder and their families.Methods:A scoping review was conducted.Results:Eigh...
More

Horticultural Therapy in Patients With Dementia: A Systematic Review and Meta-Analysis

American Journal of Alzheimer's Disease &Other Dementias®, Ahead of Print. Background:World Health Organization has communicated that dementia as a public health priority in 2012. Behavioral and psychological symptoms of dementia are the main reason results in hospitalization of dementia patients. Horticulture is one of the favorite activity for many peoples to relax their minds.Objectives:To investigate psychological health benefits of horticulture intervention in dementia patients.Methods...
More

Factors Affecting Caregivers’ Acceptance of the Use of Wearable Devices by Patients With Dementia: An Extension of the Unified Theory of Acceptance and Use of Technology Model

American Journal of Alzheimer's Disease &Other Dementias®, Ahead of Print. Purpose:This study aims to examine the factors affecting caregivers’ acceptance of the use of wearable devices by patients with dementia by extending the Unified Theory of Acceptance and Use of Technology (UTAUT) model with 2 additional constructs: resistance to change (RC) and technology anxiety (TA).Methods:A structured online questionnaire was developed and distributed to caregivers who have either dealt previousl...
More

β-Hydroxybutyrate Ameliorates Aβ-Induced Downregulation of TrkA Expression by Inhibiting HDAC1/3 in SH-SY5Y Cells

American Journal of Alzheimer's Disease &Other Dementias®, Ahead of Print. Tyrosine kinase receptor A (TrkA) plays an important role in the protection of cholinergic neurons in Alzheimer’s disease (AD). This study was designed to investigate whether β-hydroxybutyrate (BHB), an endogenous histone deacetylase (HDAC) inhibitor, upregulates the expression of TrkA by affecting histone acetylation in SH-SY5Y cells treated with amyloid β-protein (Aβ). The results showed that BHB ameliorated the re...
More

Development of an ICT-Based Dementia Care Mapping Support System and Its Usefulness Assessment

American Journal of Alzheimer's Disease &Other Dementias®, Ahead of Print. Objectives:Dementia Care Mapping (DCM) is an established practice method to implement Person-centred Care in dementia care settings. However, it is not easy to carry out DCM because of its high complexity. The aim of this study is to solve DCM complexity by adopting technology.Methods:Authors developed (1) a new information-communication technology (ICT) based DCM support system based on the investigation of difficul...
More

Feasibility of Conducting Nonpharmacological Interventions to Manage Dementia Symptoms in Community-Dwelling Older Adults: A Cluster Randomized Controlled Trial

American Journal of Alzheimer's Disease &Other Dementias®, Ahead of Print. This study assessed the feasibility of conducting 3 nonpharmacological interventions with older adults in dementia, exploring the effects of chair yoga (CY), compared to music intervention (MI) and chair-based exercise (CBE) in this population. Using a cluster randomized controlled trial (RCT), 3 community sites were randomly assigned 1:1:1 to CY, MI, or CBE. Participants attended twice-weekly 45-minute sessions for ...
More