Feasibility of Conducting Nonpharmacological Interventions to Manage Dementia Symptoms in Community-Dwelling Older Adults: A Cluster Randomized Controlled Trial

American Journal of Alzheimer's Disease &Other Dementias®, Ahead of Print. This study assessed the feasibility of conducting 3 nonpharmacological interventions with older adults in dementia, exploring the effects of chair yoga (CY), compared to music intervention (MI) and chair-based exercise (CBE) in this population. Using a cluster randomized controlled trial (RCT), 3 community sites were randomly assigned 1:1:1 to CY, MI, or CBE. Participants attended twice-weekly 45-minute sessions for ...
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Physical Activity in Severe Dementia Is Associated With Agitation Rather Than Cognitive Function

American Journal of Alzheimer's Disease &Other Dementias®, Ahead of Print. Background:The authors examined associations between physical activity, cognitive function, activities of daily living, and behavioral and psychological dementia symptoms (BPSD) in severe and moderate dementia.Methods:A cross-sectional study was conducted to assess severe and moderate dementia groups according to the Clinical Dementia Rating. An actigraphy measured physical activity. Other measures included Mini-Ment...
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Gender Differences in the Association Between Hearing Loss and Cognitive Function

American Journal of Alzheimer's Disease &Other Dementias®, Ahead of Print. Objective:This study aimed to determine the association between hearing loss and cognitive function by gender in a nationally representative sample of older adults.Methods:We used data from the National Health and Nutrition Examination Survey (2010-2011) for 655 participants aged 60 to 69 years. The cognitive functioning component consisted of the Consortium to Establish a Registry for Alzheimer’s disease, the Animal...
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Validation of the RUDAS in Patients With a Middle-Level Education in Lima, Peru

American Journal of Alzheimer's Disease &Other Dementias®, Ahead of Print. Objectives:To assess the psychometric properties of the Peruvian version of the Rowland Universal Dementia Assessment Scale (RUDAS-PE) to discriminate controls from patients with mild cognitive impairment (MCI) and early dementia (ED) in a population with a mid-level education.Methods:A total of 133 patients from a memory clinic were administered the RUDAS-PE, INECO Frontal Screening, Addenbrooke’s Cognitive Examinat...
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Cerebrospinal Fluid, Imaging, and Physiological Biomarkers in Dementia With Lewy Bodies

American Journal of Alzheimer's Disease &Other Dementias®, Ahead of Print. Dementia with Lewy bodies is a progressive neurodegenerative disorder, clinically characterized by gradual cognitive impairment and fluctuating cognition, behavioral changes and recurrent visual hallucinations, and autonomic function and movement symptoms in the type of parkinsonism. It is the second most common type of dementia in the Western world after Alzheimer disease. Over the last 20 years, many neurophysiolog...
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Impact of Zumba on Cognition and Quality of Life is Independent of APOE4 Carrier Status in Cognitively Unimpaired Older Women: A 6-Month Randomized Controlled Pilot Study

American Journal of Alzheimer's Disease &Other Dementias®, Ahead of Print. Objective:To investigate the association of a 6-month Zumba intervention with cognition and quality of life among older cognitively unimpaired apolipoprotein ∊4 (APOE4) carrier and noncarrier women.Methods:Fifty-three women were randomly assigned to either twice-weekly Zumba group classes or maintenance of habitual exercise (control group) for 6 months. At baseline, 3, and 6 months, all participants underwent neurops...
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