Age-Related Effect of Antihypertensive Treatment on Cognitive Performance: Is it Better Preventing Dementia in Older Age?

American Journal of Alzheimer's Disease &Other Dementias®, Ahead of Print. The aim of this study is to investigate the impact of optimal antihypertensive medication on cognitive function. In this 6-month clinical trial, 248 adults were randomly selected by a registry of hypertensive-treated patients (based on a National Hypertension Treatment Program), followed health centers located in Rafsanjan County, Southeast, Iran. Blood pressure was measured 3 times in each appointment pre- and postt...
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Investigation of the Effects of Biochemical Parameters on Alzheimer’s Disease

American Journal of Alzheimer's Disease &Other Dementias®, Ahead of Print. Background:The most common type of dementia is an Alzheimer’s disease which is a major concern in growing chronic diseases in the geriatric society, and its connection with biochemistry has not been sufficiently understood.Objective:This study aims to evaluate the effects of blood biochemistry on Alzheimer’s disease.Method:Eight participants aged 55+ with Alzheimer’s disease were analyzed. A cross-sectional work has ...
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The Effects of Intuitive Movement Reembodiment on the Quality of Life of Older Adults With Dementia: A Pilot Study

American Journal of Alzheimer's Disease &Other Dementias®, Ahead of Print. Background:The creative use of reminiscent music and natural movements were reported to have positive effects on the well-being of older adults with cognitive impairment.Objectives:To explore the effects of the intuitive movement reembodiment (IMR) program on the quality of life (QoL) of older adults with dementia.Methods:Data collected from 22 participants were analyzed: group 1 (mild dementia), group 2 (moderate de...
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Immediate Benefit of Art on Pain and Well-Being in Community-Dwelling Patients with Mild Alzheimer's

American Journal of Alzheimer's Disease &Other Dementias®, Ahead of Print. Objective:The present report aims to evaluate whether singing intervention can bring an immediate benefit that is greater than the one provided by painting intervention on pain and well-being.Methods:Fifty-nine mild patients with Alzheimer disease were randomized to a 12-week singing (n = 31) or painting group (n = 28). In the present analysis, the immediate evolution of pain and well-being was compared across sessio...
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The Efficacy of General Practitioner Assessment of Cognition in Chinese Elders Aged 80 and Older

American Journal of Alzheimer's Disease &Other Dementias®, Ahead of Print. Objectives:This study examined the efficacy of the General Practitioner Assessment of Cognition–Chinese version (GPCOG-C) in screening dementia and mild cognitive impairment (MCI) among older Chinese.Methods:Survey questionnaires were administered to 293 participants aged 80 or above from a university hospital in mainland China. Alzheimer disease and MCI were diagnosed in light of the National Institute on Aging and ...
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Purkinje Cells Pathology in Alzheimer’s Disease

American Journal of Alzheimer's Disease &Other Dementias®, Ahead of Print. Alzheimer’s disease (AD) is one of the main causes of dementia in senium and presenium. It is clinically characterized by memory impairment, deterioration of intellectual faculties, and loss of professional skills. The cerebellum is a critical part in the distributed neural circuits participating not only in motor function but also in autonomic, limbic, and cognitive behaviors. In present study, we aim to investigate...
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