How Evidence-Based Practice (E3BP) Informs Speech-Language Pathology for Primary Progressive Aphasia

American Journal of Alzheimer's Disease &Other Dementiasr, Volume 35, Issue , January-December 2020. Amelioration of communication impairment in primary progressive aphasia (PPA) is an area of clinical importance and current research. Speech-language pathologists (SLPs) have a range of skills and interventions to support communication in PPA; however, underrecognition of their role and low referral rates is an ongoing concern. The E3BP conceptualization of evidence-based practice comprises ...
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Insulin Resistance Is Independently Associated With Enlarged Perivascular Space in the Basal Ganglia in Nondiabetic Healthy Elderly Population

American Journal of Alzheimer's Disease &Other Dementiasr, Volume 35, Issue , January-December 2020. Objectives:To investigate the association between insulin resistance (IR) and enlarged perivascular space (EPVS) in the basal gangliain nondiabetic healthy elderly population.Methods:A total of 235 nondiabetic healthy elderly population were recruited. A 3-level scale was used to evaluate the burden of EPVSs. The homeostasis model assessment–estimated insulin resistance index (HOMA-IR) was u...
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BESI: Behavioral and Environmental Sensing and Intervention for Dementia Caregiver Empowerment—Phases 1 and 2

American Journal of Alzheimer's Disease &Other Dementiasr, Volume 35, Issue , January-December 2020. Background and Objectives:Caregiver burden associated with dementia-related agitation is one of the commonest reasons a community-dwelling person with dementia (PWD) transitions to a care facility. Behavioral and Environmental Sensing and Intervention for Dementia Caregiver Empowerment (BESI) is a system of body-worn and in-home sensors developed to provide continuous, noninvasive agitation ...
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Combined Influences of Dementia Exposure and Personality on Self-Reported Memory Problems

American Journal of Alzheimer's Disease &Other Dementiasr, Volume 35, Issue , January-December 2020. The current study investigated whether having a first-degree relative with dementia influenced older adults’ self-reported memory, if personality traits moderated these associations, and whether these associations differed by the type of item asked (ie, frequency of memory problems vs perceived memory decline). Data drawn from the Einstein Aging study included 454 older adults (M age = 76.64...
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Antidiabetic Drugs for the Risk of Alzheimer Disease in Patients With Type 2 DM Using FAERS

American Journal of Alzheimer's Disease &Other Dementiasr, Volume 35, Issue , January-December 2020. Alzheimer disease (AD) may develop after the onset of type 2 diabetes mellitus (T2DM), and the risk of AD may depend on the antidiabetic drug administered. We compared the risk of AD among 66 085 patients (≥ 65 years) with T2DM (1250 having concomitant AD) who had been administered antidiabetic drug monotherapy for T2DM who had voluntarily reported themselves in the Food and Drug Administrat...
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