Therapeutic Potential of Neu1 in Alzheimer’s Disease Via the Immune System

American Journal of Alzheimer's Disease &Other Dementiasr, Volume 36, Issue , January-December 2021. Alzheimer’s Disease (AD) is pathologically characterized by the accumulation of soluble oligomers causing extracellular beta-amyloid deposits in form of neuritic plaques and tau-containing intraneuronal neurofibrillary tangles in brain. One proposed mechanism explaining the formation of these proteins is impaired phagocytosis by microglia/macrophages resulting in defective clearance of solub...
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Association Between Oral Health and the Medical Costs of Dementia: A Longitudinal Study of Older Japanese

American Journal of Alzheimer's Disease &Other Dementiasr, Volume 36, Issue , January-December 2021. Objective:Oral health status may be associated with dementia, which in turn results in higher medical costs among older people.Methods:This STUDY enrolled 4,275 older individuals. Generalized linear models were constructed with the medical costs of dementia as the dependent variable, and number of teeth, Community Periodontal Index (CPI), and other factors as independent variables.Results:In...
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The Relationship Between Lower Urinary Tract Symptoms and Severity of Alzheimer’s Disease

American Journal of Alzheimer's Disease &Other Dementiasr, Volume 36, Issue , January-December 2021. Introduction:Urinary incontinence (UI) is more prevalent in elderly populations with dementia than those without dementia. Alzheimer’s disease (AD) is the most common cause of dementia. Urge UI, the most common type of UI in AD patients, causes more morbidity and mortality. However, it is inconvenient to obtain the report of urodynamic study from AD patient to diagnose urinary incontinence. ...
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A 2-Study Psychometric Evaluation of the Modified Dementia Worry Scale

American Journal of Alzheimer's Disease &Other Dementiasr, Volume 36, Issue , January-December 2021. A modified version of the Dementia Worry Scale (DWS) used the terminology “Alzheimer’s disease and related dementias” (versus the DWS’ use of “dementia”). Two studies investigated psychometric properties of the modified DWS (MDWS). Study 1 compared the psychometric properties of the DWS and MDWS; both versions had single factor structures and exhibited excellent internal consistency (αs ≥ .9...
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Examining Depression Symptoms With/Without Coexisting Anxiety Symptoms in Community-Dwelling Persons With Dementia

American Journal of Alzheimer's Disease &Other Dementiasr, Volume 36, Issue , January-December 2021. Depression and anxiety are common in persons with dementia (PWD) and associated with poor outcomes. We explored frequency, pharmacologic management and mental health service use in PWD and depression symptoms with/without coexisting anxiety symptoms. The sample comprised 160 community-dwelling PWD in a trial to prevent development of aggression. Baseline data on depression and anxiety sympto...
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Turkish Version of the Test Your Memory (TYM-TR) as a Screening Tool in Memory Clinics

American Journal of Alzheimer's Disease &Other Dementiasr, Volume 36, Issue , January-December 2021. Introduction:This study compared the Turkish version of Test Your Memory (TYM) MMSE (Mini-Mental State Examination) and CDT (Clock Drawing Test) in patients with neurocognitive disorder.Methods:After a thorough medical workup, patients with a diagnosis of neurocognitive disorder were enrolled. A cross-sectional design was used to compare the TYM results with those of MMSE and CDT.Results:Thi...
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